黄片看片神器

UniSQ Logo
The current and official versions of the course specifications are available on the web at .
Please consult the web for updates that may occur during the year.

BIO2107 Cell and Molecular Biology 1

Semester 1, 2023 External
Units : 1
School or Department : School of Agriculture and Environmental Science
Grading basis : Graded
Course fee schedule : /current-students/administration/fees/fee-schedules

Staffing

Course Coordinator:

Requisites

Pre-requisite: CHE2120

Overview

An understanding of the theory and techniques of cell and molecular biology are becoming an essential component in the research and medical diagnostic spheres. The course will provide the student with theoretical knowledge in basic molecular biology and cell biology. During the course students will gain an insight into the nature of cellular substructure, vesicle trafficking, protein post-translational modifications and targeting and control of the cell cycle. The students will also explore the nature of cells at the molecular level as well as the current molecular technologies that enable such information to be derived. Finally, the students will gain knowledge of the nature of the molecular and other technologies that have advanced the analytical options in a research laboratory.

The course is presented in two modules: in the first, the course introduces the nature of gene organisation, replication and expression in both prokaryotic and eukaryotic systems. The course also provides an overview of molecular technologies including recombinant DNA techniques and standard molecular methods such as sequencing, RNAi, CRISPR-Cas9, in situ hybridisation, northern and western Blot assays, PCR, rtPCR and qPCR. These procedures underpin state of the art research and medical diagnostic assays. Applications of this technology are discussed. In the second module the course explores the nature of cellular ultrastructure; protein post-translational modification and targeting; vesicle transport in cells; regulation of the cell cycle and apoptosis.

This course contains a highly recommended residential school for both external and on-campus students (non-attendance will mean the student misses both an element for assessment preparation and an element of assessment).

Course learning outcomes

On completion of this course students will be able to:

  1. describe the current concepts of DNA structure maintenance and repair;
  2. explain the basic processes involved in gene replication, transcription and translation in both prokaryotic and eukaryotic systems;
  3. compare basic tools used in recombinant DNA technology including: enzymes, plasmids and techniques for cloning and characterisation;
  4. explain the practical application of a range of basic molecular techniques including sequencing, RNAi, CRISPR-Cas9, in situ hybridisation, northern and western Blot, PCR, rtPCR and qPCR;
  5. describe processes of post-translational protein modification;
  6. compare and contrast the role of the cytoskeleton and the structure, function and maintenance of cell organelles;
  7. explain cellular trafficking, cell cycle control mechanisms and apoptosis.

Topics

Description Weighting(%)
1. Genome organisation in prokaryotic and eukaryotic cells 8.00
2. DNA replication and repair 8.00
3. Translation 8.00
4. Gene expression in prokaryotes 4.00
5. Gene expression in eukaryotes 12.00
6. Recombinant DNA techniques 4.00
7. Cell & molecular applications in a research laboratory 12.00
8. Post-translational protein modification 8.00
9. Protein sorting and targeting 8.00
10. Intracellular compartmentalisation 8.00
11. Cellular cytoskeleton 8.00
12. Cell cycle control and apoptosis 12.00

Text and materials required to be purchased or accessed

Iwasa J and Marshall W 2020, Karp's Cell and Molecular Biology: Concepts and Experiments, 9th edn, John Wiley, New York.

Student workload expectations

To do well in this subject, students are expected to commit approximately 10 hours per week including class contact hours, independent study, and all assessment tasks. If you are undertaking additional activities, which may include placements and residential schools, the weekly workload hours may vary.

Assessment details

Approach Type Description Group
Assessment
Weighting (%) Course learning outcomes
Assignments Written Quiz A1 of 3 No 10 1
Assignments Written Quiz A2 of 3 No 20 2,3,4
Assignments Oral Presentation (ind, grp, mltmd) No 20 4
Assignments Written Report No 20 3,4,5,7
Assignments Written Quiz A3 of 3 No 30 5,6,7
Date printed 9 February 2024